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Generic Prozac Fluoxetine. Mechanism of Action

Prozac (generic Fluoxetine) is the main representative of a selective inhibitors group. It has a stimulating effect. It does not cause sedation, orthostatic hypotension, is non-cardiotoxic. The drug is used for treating depression, bulimia, obsessive-compulsive disorders and premenstrual syndrome.

The drug is produced in the form of capsules with Fluoxetine as an active substance. Prozac helps to perk up the mood, to lessen feelings of fear and anxiety, to eliminate dysphoria. It starts bringing about a lasting effect after 1-2 weeks. This drug is considered to be the world's best anti-depressant.

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Nowadays, it has a dominant position in the pharmacological market.

Prozac generic is well absorbed from the gastrointestinal tract - up to 95% of the dose taken. If taken with food it slightly inhibits the Fluoxetine absorption. The effect of initial passage through the liver is low-grade. The drug is quite well accumulated in the tissues and easily penetrates through the BBB.

It takes quite a long time for the medication to develop the desired effect. But it can be very noticeable. Prozac's effect is achieved gradually, then it reaches a certain level, which remains the same even with the reduction of the medicament doses. Shy people become more confident, those who are sensitive become more steadfast, pessimists become optimists.

Prozac has amazing properties. Therefore, it becomes clear why this drug is prescribed for treating social phobia, panic attacks and other anxiety disorders so often. The medicament helps people to gain confidence which they lacked before. Prozac's positive effect has been experimentally proven on rats.

This drug's obvious advantage is that it doesn't cause addiction. It doesn't have side effects that previous antidepressants had. Another advantage is that even a huge overdose causes no fatal result. There have been cases when people were trying to commit a suicide by taking from 50 to 100 pills and yet stayed alive.

Everyone feels himself frustrated or unhappy at times. In some people's case their emotions can seriously affect their lives. They need taking various drugs and antidepressants to come back to their normal state of mind and get rid of the panic mood. Prozac which is an effective tool in the fight against depression would be an ideal solution in such cases.

How do the antidepressants help?

Patients who take antidepressants feel significant improvement even after the first few months of therapy. However, they can only help to get rid of the symptoms of mental illness, but the others incurable aspects of disease remain. Typically, antidepressants are only able to adjust the work of mechanisms of the brain, consisting of a large number of neurons.

The nerve cells are connected to each other without touching. Between them there is a synaptic cleft. Transmission of information from neuron to the other particle of the brain and its transfer across the synapse is carried out by a so-called mediator.

Depression - a condition in which concentration of chemical mediators in the brain is reduced. Antidepressants regulate the concentration of these substances and bring them into balance. Thus, the work of some of the brain mechanisms (neurotransmitters including) is corrected.

Effect of the drug usually begins within 2-3 weeks after start of the treating. Sometimes changes of the mood for the better are observed after 7 days. Antidepressants act on each patient differently. For some patients it is simply a panacea.

For other patients, these drugs can help to get rid of only some depressive symptoms. And there are people for whom such medicinal products did not have any effect. However, it is worth noting that modern antidepressants are not addictive. They only help our bodies to restore the broken mechanisms of the brain.

Before Use Prozac generic Fluoxetine. Precautions

Before taking Prozac, consult a doctor. The specialist will:

  • choose the optimal intake for you
  • foresee all the unwanted effects.

The further described nuances should be considered before prescribing this antidepressant.

In the treatment of patients with underweight the anorexigenic effects of Prozac need to be evaluated, as there may be rapid and progressive weight loss. Appointment of fluoxetine (which is an active ingredient of Prozac) for patients with diabetes increases the risk of hyperglycemia and hypoglycemia in case of its cessation. Therefore, the dose of insulin and/or any other hypoglycemic medications intended for internal use that are taken has to be adjusted.

Up to the moment when there is a significant improvement in the treatment, patients should be monitored by a doctor. During the treatment, the patient has to avoid taking ethanol and involving in potentially hazardous activity (meaning activities that require attention and fast motor, mental reactions).

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You must wait at least fourteen days after stopping an MAO inhibitors before you can take Fluoxetine. After stopping treatment with fluoxetine, MAO inhibitors can be taken in no less than five weeks. If a patient is elderly and has any disease, treatment should be started with half a dose.

After getting acquainted with these recommendations, you will be able to provide a secure taking of Prozac and increase its efficacy. However, the decision has to be made by a doctor.

Usage and dosage of Prozac (generic Fluoxetine)

The standard capsule of the drug Prozac contains 40 mg of the substance Fluoxetine. It is ingested orally without chewing. It is advisable to take this drug with meals and in the morning. Also there was not established the need to change the Prozac dosage according to the patient's age. But in cases of impaired hepatic function and concomitant diseases or if taking other drugs, the dose and the number of doses should be reduced.

In the case of diagnosis of depression in the initial stage the daily dose is 40 mg (1 capsule).

The diagnosis of bulimia nervosa requires taking 60 mg of the drug per day.

When obsessive-compulsive disorders an initial daily dose is 20-60 mg.

And during the premenstrual dysphoric disorders the Prozac dosage per day is also 20 mg.

The recommended daily dose may be reduced or increased at the discretion of the treating physician. But it should not exceed 80 mg per day. Because of the fact that researches with such Prozac dosage have not been clinically studied yet.

Stable clinical effect is observed within the first or second week of treatment. A full course of treatment is only 3-4 weeks.

In case of Prozac overdose there may be nausea, vomiting, and seizures, and increased arousal. In this case you should wash out the stomach, take activated charcoal, and when convulsions - tranquilizers (anxiolytic drugs). Also a symptomatic therapy is prescribed.

Prozac generic Fluoxetine contraindications

Prozac is a widely used antidepressant that has an international name - Fluoxetine. Only a doctor can prescribe the right dosage of the drug, taking into account your medical condition and Prozac contraindications. Drug has a beneficial effect at depression in mild, moderate and severe forms. Effectiveness of the drug is marked with treatment of bulimia, anorexia, alcoholism and compulsive. Medication is available in capsules.

Pharmacological action of Prozac is based on selective serotonin reuptake inhibitor. The result of its impact is improvement of mood, reduction of tension, anxiety and fear, eliminating dysphoria. The drug does not cause hypotension, sedation, no cardiotoxic.

Taking into account Prozac contraindications, the drug should be taken with caution, not more than 20 mg per day, in the mornings. Maximum permissible daily dose is 80 mg. For elderly patients the daily dosage should be less than 60 mg per day in 3 divided doses. Patients usually feel better after 3-4 weeks of using the drug.

There are several contraindications of the generic Prozac:

  • hypersensitivity to the drug components
  • suicidal tendencies
  • chronic liver and renal failure
  • simultaneous use of MAO inhibitors
  • pregnancy and lactation.

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The drug should be taken with caution at diabetes, epileptic syndrome, Parkinson's disease. Like many of antidepressant, among Fluoxetine contraindications there is the presence of reactions of the body to the drug such as dizziness, insomnia, headache, fatigue, tremor, anxiety, delusions. The digestive system may react by decreasing appetite, dry mouth, nausea, diarrhea.

There may be some allergic reactions such as rash or hives. Need to follow the regime of drug taking and avoid overdosing. In the case of the above symptoms it should be washed stomach, take activated charcoal and conduct a symptomatic therapy.

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Although depression can cause you to feel hopeless, help is available. Talk to your doctor about medications for the treatment of depression. If you are interested in buying Prozac online or from a local pharmacy and taking this drug to treat your depression symptoms, your doctor can provide you with the necessary prescription. Save a lot of money on your medication, and buy discount Prozac online or cheap Fluoxetine online from BuyProzacOnline.n.nu. You will appreciate our lowest price guarantee.

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